Programme
14 Jun 2023 (Wed) Venue: N21 – G013 Lecture Hall Day 1 – PM |
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Session ONE Exchange Session on Biomedical Sciences between Faculty of Health Sciences, University of Macau and International School of Medicine, Zhejiang University |
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Session Chair(s)
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14:30-14:35 |
Opening speech delivered by Prof. Chuxia DENG
Dean of the Faculty of Health Sciences of the University of Macau
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14:35-14:40 |
Opening speech delivered by Dr. Wei LI
Deputy Secretary of the Communist Party Committee, The Fourth Affiliated Hospital, Zhejiang University School of Medicine &
International School of Medicine, Zhejiang University
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14:40-15:00 |
![]() Qiming SUN Talk title: Cholesterol Metabolism Integrates ER Homeostasis and Innate Immunity |
15:00-15:20 |
![]() Dante NECULAI Talk title: Excess Plasmalemmal Cholesterol Activates a Gαq/PLCβ3 Relay to Induce the Formation of E-SYT1-dependent ER-PM Contact Sites |
15:20-15:40 |
![]() Xin LI Talk title: A Conserved Small RNA-based Genome Integrity Protection Mechanism |
15:40-16:00 |
![]() Bingbing WU Talk title: Endometrial Development and Regeneration |
16:00-16:30 | Coffee Break |
16:30-16:50 |
![]() Edwin Chong Wing CHEUNG Talk title: Nuclear Receptor Coregulator Function in Nuclear Hormone-Dependent Cancers |
16:50-17:10 |
![]() Gang LI Talk title: Deciphering the Metabolic-epigenetic Crosstalk: AMPK’s Impact on TET2 and Transcriptional Regulation of Pax7 |
17:10-17:30 |
![]() Fangyuan SHAO Talk title: Reversal of Broad Drug Resistance Through Increasing Mitochondrial OXPHOS to Induce Protein Neosynthesis |
17:30-17:50 |
![]() Guokai CHEN Talk title: Metabolic Regulation on Pluripotency and Cell Fate Determination |
18:30 (TBC)-20:00 | Welcome Reception Venue: 木偶葡國餐廳 |
15 Jun 2023 (Thu) Venue: N2 – University Hall Day 2 – AM |
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08:30-09:00 | Registration/ Guest Reception |
Opening Ceremony of the Ninth Macau Symposium on Biomedical Sciences | |
09:00-09:30 |
Welcome Remarks delivered by Prof. Yonghua SONG
Rector of the University of Macau
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Address delivered by Mr. Kun Wai CHEANG
Acting President of the Administrative Committee of the Science and Technology Development Fund
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Programme Introduction delivered by Prof. Chuxia DENG
Dean of the Faculty of Health Sciences of the University of Macau
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Group Photo
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Plenary Session ONE |
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Session Chair(s)
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09:30-10:10 |
![]() Keynote Speaker: Mien-Chie HUNG Talk title: Marker-guided Effective Therapy (Mget) |
10:10-10:40 |
![]() Weihong TAN Talk title: Molecular Mapping for Digitizing Single Cell |
10:40-11:10 |
![]() Fan ZHANG Talk title: Second Near-Infrared Window Fluorescent Probes for In Vivo Multiplexed Bioimaging |
11:10-11:40 | Coffee Break |
11:40-12:10 |
![]() Liang TONG Talk title: Molecular Insights into Human RNA 3’-end Processing and Relevance for Cancer Drug Discovery |
12:10-12:40 |
![]() Yehuda G. ASSARAF Talk title: Lysosomal Biogenesis and Exocytosis as a Novel Target to Surmount Cancer Multidrug Resistance |
12:40-14:30 | Luncheon sponsored by 星創盈數碼科技工程一人有限公司 and Poster Session Venue: N1 – Multi-function Hall |
15th June 2023 (Thu) Day 2 – PM |
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14:30-16:00 | Session TWO C. elegans Cell Biology: Membrane, Cytoskeleton and Organelle |
Session THREE Development of Smart Therapeutics and Drug Delivery Systems |
Venue: N2 – University Hall |
Venue: N1 – Multi-function Hall |
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Session Chair(s)
![]() Hongjie ZHANG |
Session Chair(s)
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![]() Guangshuo OU Talk title: Regulation of Intraflagellar Transport and Ciliopathies |
![]() Wei TAO (Online) Talk title: Nano-/Microscale Materials-enabled Drug Delivery Technologies |
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![]() Xiaochen WANG Talk title: Maintenance of Lysosome Integrity and Function in C. Elegans |
![]() Jinyao LIU (Online) Talk title: Bacteria-based Therapeutics |
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![]() Chonglin YANG Talk title: Understanding Metabolic Damage of Mitochondria |
![]() Feng QIAN Talk title: High Concentration Therapeutic Proteins: From Formulation Optimization to Protein Design |
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![]() Anbing SHI Talk title: How Cell Stabilizes Endosomal F-actin? |
![]() Zhen GU (Online) Talk title: Bioresponsive Drug Delivery |
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16:00-16:30 | Coffee Break and Poster Session Venue: N2 – University Hall |
Coffee Break and Poster Session Venue: N1 – Multi-function Hall |
16:30-18:00 | Session FOUR Cancer Reserch and Therapy Development |
Session FIVE Biology of Aging |
Venue: N2 – University Hall |
Venue: N1 – Multi-function Hall |
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Session Chair(s)
![]() Kathy Qian LUO |
Session Chair(s)
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![]() Hanry YU Talk title: Contextual AI Approach of Classifying Earlier GI Tract Diseases |
![]() Zhongjun ZHOU Talk title: Disorganized Chromatin Hierarchy Drives Stem Cells Aging in Atypical Laminopathy-based Progeria Mandibuloacral dysplasia type A |
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![]() Karl TSIM Talk title: Phytochemicals Regulate Angiogenic Functions in Endothelial Cells by Binding to Vascular Endothelial Growth Factor (VEGF): Drug Development Targeting to Cancer Therapy |
![]() Yidong SHEN Talk title: The Trigger of the Germline Longevity |
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![]() Peng CHEN Talk title: Imaging Guided Multimodal Cancer Therapy Based on Nano-Multizymes |
![]() Haiying LIU Talk title: Telomere Stability Regulation and Cellular Senescence |
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![]() Godefridus J (Frits) PETERS Talk title: Co-cultured Spheroids as Model Systems for Tumour Micro-environment and Drug Testing |
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![]() Kathy Qian LUO Talk title: Elucidating How Circulating Tumor Cells Resist Fluidic Shear Stress in Circulation and Acquire Stronger Metastatic Capacities |
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18:30-21:00 | Gala Dinner Venue: 港澳德興火鍋海鮮酒家 |
16 Jun 2023 (Fri) Day 3 – AM |
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09:00-10:30 | Session SIX Drug Discovery and Biomaterials for Immune Regulation |
Session SEVEN Stem Cell, Gene & Cell Therapy |
Venue: N2 – University Hall |
Venue: N1 – Multi-function Hall |
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Session Chair(s)
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Session Chair(s)
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![]() Yongjun DANG Talk title: Discovery of Small Molecules for |
![]() Ji DONG Talk title: A Single-nucleus Survey of Mammalian Hibernation for Liver Protection |
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![]() Liang CHEN Talk title: Proteostasis and Antitumour Immunity |
![]() Junjiu HUANG Talk title: Gene Editing Therapy of β-Thalassemia |
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![]() Daishun LING Talk title: Dynamic Nano-Assemblies-based Biomaterials and Drug Delivery Systems |
![]() Wanze CHEN Talk title: Live-seq Enables Temporal Transcriptomic Recording of Single Cells |
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![]() Haijun YU Talk title: Smart Nanomedicine for Cancer Immunotherapy |
![]() Xiaoyang ZHAO Talk title: Understanding and Managing of Male Infertility Based on Mechanism Study |
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![]() Chengtie WU (Online) Talk title: 3D Printing of Biomimetic Biomaterials and Cells |
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10:30-11:00 | Coffee Break and Poster Session Venue: N2 – University Hall |
Coffee Break and Poster Session Venue: N1 – Multi-function Hall |
11:00-12:30 | Session EIGHT Cell Death |
Session NINE G protein-Coupled Receptor: Structure, Signaling, and Diseases |
Venue: N2 – University Hall |
Venue: N1 – Multi-function Hall |
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Session Chair(s)
![]() Hanming SHEN |
Session Chair(s)
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![]() Liming SUN Talk title: Necroptosis on the Brake |
![]() Yang DU Talk title: Structure, Function and Drug Disovery of G Protein-coupled Receptor in Nervous System |
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![]() Sudan HE Talk title: The Role of RIPK1/RIPK3 in Inflammatory Responses Associated with GVHD |
![]() Sookja Kim CHUNG Talk title: Exchange Proteins Activated by Cyclic AMP and Their Role in Diverse Function and Diseases |
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![]() You-Sun KIM Talk title: Necroptosis: Molecular Mechanisms and Disease Implications |
![]() Hsien-Da HUANG Talk title: Multi-omics in MicroRNA-related Biomarker and Drug Target Discovery |
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![]() Francis Kaming CHAN Talk title: Immunogenic Cell Death: The Good, the Bad and the Ugly |
![]() Pei-Gen REN Talk title: Development of Oral Polypeptide Drug Targeting GPRC6A for Nonalcoholic Steatohepatitis |
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![]() Yung Hou WONG Talk title: Preferential Binding of G Protein to the MT1 Protomer of the MT1/MT2 Heterodimeric Melatonin Receptor Complex |
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12:30-14:30 | Luncheon sponsored by Thermo Fisher Scientific (Hong Kong) Limited and Poster Session Venue: N1 – Multi-function Hall |
16th Jun 2023 (Fri) Day 3 – PM |
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14:30-16:30 | Coffee Break and Poster Session Venue: N1 – Multi-function Hall |
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16:30-18:00 | Session TEN Molecular Mechanism and Precise Diagnosis and Treatment of Cancer |
Session ELEVEN Spatial Omics Biology |
Venue: N2 – University Hall |
Venue: N1 – Multi-function Hall |
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Session Chair(s)
![]() Kai MIAO |
Session Chair(s)
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![]() Yuan LIU Talk title: Nanoproteomics-based Biomarker Discovery and Cancer Diagnostics |
![]() Longqi LIU Talk title: Large-field of View, High-Resolution Spatially Resolved Transcriptomics Using DNA Nanoball Patterned Array |
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![]() Jiangjiang QIN Talk title: Targeting UPS for Cancer Therapy: New Mechanisms and New Strategies |
![]() Xianting DING Talk title: Single Cell Proteomic Analysis Techniques and Clinical Applications |
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![]() Xiangsheng LIU Talk title: Tumor Targeting Aptamer Drug Conjugate and Nano Drug Delivery System |
![]() Xiang ZHOU Talk title: Statistical Methods for Spatial Transcriptomics |
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![]() Ji JING Talk title: Design Optogenetic Toolbox for Deep Understanding Intracellular Organelles Communications and Remote Control of Programmed Cell Death |
17 Jun 2023 (Sat) Day 4 – AM |
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09:00-10:30 | Session TWELVE TCM and Natural Product-based Drug Discovery |
Session THIRTEEN Targeting Gut Microbiota and Metabolism for Cancer Immunomodulation |
Venue: N2 – University Hall |
Venue: N1 – Multi-function Hall |
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Session Chair(s)
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Session Chair(s)
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![]() Hong PENG (Online) Talk title: Roles of University Technology Transfer in Biomedical Business |
![]() Xiang ZHANG Talk title: Gut Microbiota, Metabolites and Fatty Liver Diseases |
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![]() Jinhua WANG (Online) Talk title: The Study on Anti-Glioblastoma Effect and Its Mechanism of Sinomenine Ester Derivative |
![]() Yuting YANG on behalf of Hong WEI Talk title: Humanized Germ-free Animal Models and Their Roles in the Study of Microbiome Related Tumor Genesis and Development and Immunotherapy |
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![]() Hubing SHI Talk title: Immune Checkpoint HLA-E:CD94-NKG2A Mediates Evasion of Circulating Tumor Cells from NK Cell Surveillance |
![]() Di LIU Talk title: Intestinal Microbiome and Disease Health |
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![]() Liwu FU Talk title: Progress in the Personalization of Tumour Chemotherapeutic Drug |
![]() Carmen Chak-Lui WONG Talk title: Precision Medicine and the Mechanistic Basis of Combination Treatments for Liver Cancer |
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![]() Hoi Leong Xavier WONG Talk Title: Therapeutic Targets of Metabolic Disorders- What’s New? |
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10:30-11:00 | Coffee Break and Poster Session Venue: N2 – University Hall |
Coffee Break and Poster Session Venue: N1 – Multi-function Hall |
11:00-12:30 | Session FOURTEEN Molecular Probes and Biosensors |
Session FIFTEEN Neuroscience, Aging and Degenerative Diseases |
Venue: N2 – University Hall |
Venue: N1 – Multi-function Hall |
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Session Chair(s)
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Session Chair(s)
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![]() Zhizeng GAO Talk title: Development of Fluorescent Polarization-based High Throughput Screening Assays |
![]() Qing WANG Talk title: Neurovascular Unit Roles in Neurodegeneration |
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![]() Zonghai SHENG Talk title: Recent Advances in ICG Near-Infrared Fluorescence Molecular Imaging in the Second Biowindow |
![]() Xintong LIU Talk title: Research Progress in Prehospital Neuroprotection of Acute Stroke. |
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![]() Xiaoqiang CHEN Talk title: Functional Dyes for Imaging and Detection Applications |
![]() Xifei YANG Talk title: Adiponectin Deficiency Accelerates Brain Aging via Mitochondria-associated Neuroinflammation |
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![]() Peng GUO Talk title: Spatiotemporal Visualization of Bystander Activity of Antibody Drug Conjugates for Enhancing Solid Tumour Penetration |
![]() Haiwei HUANG Talk title: Effect of Vestibular Dysfunction on Cognition |
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![]() Jiangang SHEN Talk title: Hypochlorous Acid Derived from Microglial Myeloperoxidase Mediates High-mobility Group Box 1 Release from Neurons to Amplify Brain Damage in Cerebral Ischemia-reperfusion Injury |
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12:30-14:30 | Luncheon sponsored by LingBio Biotechnology Macau Company Ltd and Poster Session Venue: N1 – Multi-function Hall |
17th Jun 2023 (Sat) Venue: N2 – University Hall Day 4 – PM |
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Plenary Session TWO |
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Session Chair(s)
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14:30-15:10 |
![]() Keynote Speaker: Dennis LO Talk title: Creating Paradigms Shift in Molecular Diagnostics |
15:10-15:40 |
![]() Alexander HOFFMANN Talk title: A Temporal Signaling Code to Specify Immune Responses |
15:40-16:10 |
![]() Gourisankar GHOSH Talk title: Diverse Nuclear Factors are Enablers of NF-kB’s Transcriptional Activity |
16:10-16:40 | Coffee Break |
16:40-17:10 |
![]() Hong ZHANG Talk title: Liquid–liquid Phase Separation in Autophagy |
17:10-17:40 |
![]() Richard J. YOULE Talk title: Mitochondria Quality Control and Parkinson’s Disease |
17:40-18:10 | Short talk for poster |
18:10-18:30 | Best Poster Awards |
Closing Ceremony of the Ninth Macau Symposium on Biomedical Sciences | |
Closing Speech by Prof. Renhe XU
Associate Dean of the Faculty of Health Sciences of the University of Macau
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