Programme

The tentative programme run down of “9th Macau Symposium on Biomedical Sciences 2023” as follows:

This year’s symposium will be held in a format that combines online (via ZOOM) and in-person elements, in order to allow participants from around the world to participate in the event.

Participants who are unable to attend the symposium in person can join the meeting on ZOOM. ZOOM ID and password will be provided after registration.

	15^th Jun 2023 (THU) – AM		16^th Jun 2023 (FRI) – AM		17^th Jun 2023 (SAT) – AM
	Venue: U-Hall		Venue: U-Hall and Multi-function Hall		Venue: U-Hall and Multi-function Hall
	09:00 – 09:30 Opening Ceremony		09:30 – 12:30		09:30 – 12:30
	Plenary Session ONE		Concurrent Session 6	Concurrent Session 7	Concurrent Session 12	Concurrent Session 13
			Coffee Break & Poster Session		Coffee Break & Poster Session
			Concurrent Session 8	Concurrent Session 9	Concurrent Session 14	Concurrent Session 15
	12:30 – 14:00 Lunch & Poster Session		12:30 – 14:00 Lunch & Poster Session		12:30 – 14:00 Lunch & Poster Session
14^th Jun 2023 (WED) – PM	15^th Jun 2023 (THU) – PM		16^th Jun 2023 (FRI) – PM		17^th Jun 2023 (SAT) – PM
Venue: N21 – G013 Lecture Hall	Venue: U-Hall and Multi-function Hall		Venue: U-Hall and Multi-function Hall		Venue: U-Hall
14:30 – 18:00	14:30 – 18:00		14:30 – 18:00		14:30 – 18:00
Session 1	Concurrent Session 2	Concurrent Session 3	Poster Session Short talk for poster		Plenary Session TWO
Seminar Series of Faculty of Health Sciences, University of Macau and College of Life Sciences, Zhejiang University on Biomedical Sciences	Coffee Break & Poster Session		Coffee Break & Poster Session
	Concurrent Session 4	Concurrent Session 5	Concurrent Session 10	Concurrent Session 11	Best Poster Award
					Closing Ceremony
	Gala Dinner

14 Jun 2023 (Wed)

14 Jun 2023 (Wed) Venue: N21 – G013 Lecture Hall Day 1 – PM
Session ONE Exchange Session on Biomedical Sciences between Faculty of Health Sciences, University of Macau and International School of Medicine, Zhejiang University
Session Chair(s) Kai MIAO Faculty of Health Sciences, University of Macau Aifu LIN International School of Medicine, Zhejiang University
14:30-14:35	Opening speech delivered by Prof. Chuxia DENG Dean of the Faculty of Health Sciences of the University of Macau
14:35-14:40	Opening speech delivered by Dr. Wei LI Deputy Secretary of the Communist Party Committee, The Fourth Affiliated Hospital, Zhejiang University School of Medicine & International School of Medicine, Zhejiang University
14:40-15:00	Qiming SUN International School of Medicine, Zhejiang University Talk title: Cholesterol Metabolism Integrates ER Homeostasis and Innate Immunity
15:00-15:20	Dante NECULAI International School of Medicine, Zhejiang University Talk title: Excess Plasmalemmal Cholesterol Activates a Gα_q/PLCβ₃ Relay to Induce the Formation of E-SYT1-dependent ER-PM Contact Sites
15:20-15:40	Xin LI International School of Medicine, Zhejiang University Talk title: A Conserved Small RNA-based Genome Integrity Protection Mechanism
15:40-16:00	Bingbing WU The Fourth Affiliated Hospital, Zhejiang University, School of Medicine Talk title: Endometrial Development and Regeneration
16:00-16:30	Coffee Break
16:30-16:50	Edwin Chong Wing CHEUNG Faculty of Health Sciences, University of Macau Talk title: Nuclear Receptor Coregulator Function in Nuclear Hormone-Dependent Cancers
16:50-17:10	Gang LI Faculty of Health Sciences, University of Macau Talk title: Deciphering the Metabolic-epigenetic Crosstalk: AMPK’s Impact on TET2 and Transcriptional Regulation of Pax7
17:10-17:30	Fangyuan SHAO The University of Macau Talk title: Reversal of Broad Drug Resistance Through Increasing Mitochondrial OXPHOS to Induce Protein Neosynthesis
17:30-17:50	Guokai CHEN Faculty of Health Sciences, University of Macau Talk title: Metabolic Regulation on Pluripotency and Cell Fate Determination
18:30 (TBC)-20:00	Welcome Reception Venue: 木偶葡國餐廳

15 Jun 2023 (Thu)

15 Jun 2023 (Thu) Venue: N2 – University Hall Day 2 – AM
08:30-09:00	Registration/ Guest Reception
Opening Ceremony of the Ninth Macau Symposium on Biomedical Sciences
09:00-09:30	Welcome Remarks delivered by Prof. Yonghua SONG Rector of the University of Macau
	Address delivered by Mr. Kun Wai CHEANG Acting President of the Administrative Committee of the Science and Technology Development Fund
	Programme Introduction delivered by Prof. Chuxia DENG Dean of the Faculty of Health Sciences of the University of Macau
	Group Photo
Plenary Session ONE
Session Chair(s) Chuxia DENG Faculty of Health Sciences, University of Macau
09:30-10:10	Keynote Speaker: Mien-Chie HUNG China Medical University Talk title: Marker-guided Effective Therapy (Mget)
10:10-10:40	Weihong TAN The Institute of Basic Medicine and Cancer, Chinese Academy of Sciences Talk title: Molecular Mapping for Digitizing Single Cell
10:40-11:10	Fan ZHANG Department of Chemistry, Fudan University Talk title: Second Near-Infrared Window Fluorescent Probes for In Vivo Multiplexed Bioimaging
11:10-11:40	Coffee Break
11:40-12:10	Liang TONG Department of Biological Sciences, Columbia University Talk title: Molecular Insights into Human RNA 3’-end Processing and Relevance for Cancer Drug Discovery
12:10-12:40	Yehuda G. ASSARAF Faculty of Biology, Technion – Israel Institute of Technology Talk title: Lysosomal Biogenesis and Exocytosis as a Novel Target to Surmount Cancer Multidrug Resistance
12:40-14:30	Luncheon sponsored by 星創盈數碼科技工程一人有限公司 and Poster Session Venue: N1 – Multi-function Hall

15^th June 2023 (Thu) Day 2 – PM
14:30-16:00	Session TWO C. elegans Cell Biology: Membrane, Cytoskeleton and Organelle	Session THREE Development of Smart Therapeutics and Drug Delivery Systems
	Venue: N2 – University Hall	Venue: N1 – Multi-function Hall
	Session Chair(s) Hongjie ZHANG Faculty of Health Sciences, University of Macau	Session Chair(s) Ruibing WANG Institute of Chinese Medical Sciences, University of Macau Ying ZHENG Institute of Chinese Medical Sciences, University of Macau
	Guangshuo OU School of Life Sciences, Tsinghua University Talk title: Regulation of Intraflagellar Transport and Ciliopathies	Wei TAO (Online) Innovation (Endowed Chair) \| Brigham and Women’s Hospital; Faculty of Medicine, Harvard University Talk title: Nano-/Microscale Materials-enabled Drug Delivery Technologies
	Xiaochen WANG Institute of Biophysics, Chinese Academy of Science Talk title: Maintenance of Lysosome Integrity and Function in C. Elegans	Jinyao LIU (Online) Shanghai Jiaotong University Talk title: Bacteria-based Therapeutics
	Chonglin YANG Yunnan University Talk title: Understanding Metabolic Damage of Mitochondria	Feng QIAN School of Pharmaceutical Sciences, Tsinghua University Talk title: High Concentration Therapeutic Proteins: From Formulation Optimization to Protein Design
	Anbing SHI Huazhong University of Science and Technology Talk title: How Cell Stabilizes Endosomal F-actin?	Zhen GU (Online) College of Pharmaceutical Sciences, Zhejiang University Talk title: Bioresponsive Drug Delivery
16:00-16:30	Coffee Break and Poster Session Venue: N2 – University Hall	Coffee Break and Poster Session Venue: N1 – Multi-function Hall
16:30-18:00	Session FOUR Cancer Reserch and Therapy Development	Session FIVE Biology of Aging
	Venue: N2 – University Hall	Venue: N1 – Multi-function Hall
	Session Chair(s) Kathy Qian LUO Faculty of Health Sciences, University of Macau	Session Chair(s) Wakam CHANG Faculty of Health Sciences, University of Macau Session Co-Chair(s) Garry WONG Faculty of Health Sciences, University of Macau
	Hanry YU Mechanobiology Institute, National University of Singapore Talk title: Contextual AI Approach of Classifying Earlier GI Tract Diseases	Zhongjun ZHOU LKX Faculty of Medicine, The University of Hong Kong Talk title: Disorganized Chromatin Hierarchy Drives Stem Cells Aging in Atypical Laminopathy-based Progeria Mandibuloacral dysplasia type A
	Karl TSIM Division of Life Science, The Hong Kong University of Science and Technology Talk title: Phytochemicals Regulate Angiogenic Functions in Endothelial Cells by Binding to Vascular Endothelial Growth Factor (VEGF): Drug Development Targeting to Cancer Therapy	Yidong SHEN Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences Talk title: The Trigger of the Germline Longevity
	Peng CHEN School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University Talk title: Imaging Guided Multimodal Cancer Therapy Based on Nano-Multizymes	Haiying LIU School of Life Sciences, Sun Yat-Sen University Talk title: Telomere Stability Regulation and Cellular Senescence
	Godefridus J (Frits) PETERS Amsterdam University Medical Centers, Vrije Universiteit Amsterdam Talk title: Co-cultured Spheroids as Model Systems for Tumour Micro-environment and Drug Testing
	Kathy Qian LUO Faculty of Health Sciences, University of Macau Talk title: Elucidating How Circulating Tumor Cells Resist Fluidic Shear Stress in Circulation and Acquire Stronger Metastatic Capacities
18:30-21:00	Gala Dinner Venue: 港澳德興火鍋海鮮酒家

16 Jun 2023 (Fri)

16 Jun 2023 (Fri) Day 3 – AM
09:00-10:30	Session SIX Drug Discovery and Biomaterials for Immune Regulation	Session SEVEN Stem Cell, Gene & Cell Therapy
	Venue: N2 – University Hall	Venue: N1 – Multi-function Hall
	Session Chair(s) Yunlu DAI Faculty of Health Sciences, University of Macau Joong Sup SHIM Faculty of Health Sciences, University of Macau	Session Chair(s) Guokai CHEN Faculty of Health Sciences, University of Macau Session Co-chair(s) Ren-He XU Faculty of Health Sciences, University of Macau
	Yongjun DANG Institute of Life Sciences, Chongqing Medical University Talk title: Discovery of Small Molecules for Tumour Immuno-Regulation	Ji DONG Guangzhou National Laboratory Talk title: A Single-nucleus Survey of Mammalian Hibernation for Liver Protection
	Liang CHEN Shenzhen Institute of Advanced Technology Talk title: Proteostasis and Antitumour Immunity	Junjiu HUANG School of Life Sciences, Sun Yat-Sen University Talk title: Gene Editing Therapy of β-Thalassemia
	Daishun LING School of Chemistry and Chemical Engineering, Shanghai Jiaotong University Talk title: Dynamic Nano-Assemblies-based Biomaterials and Drug Delivery Systems	Wanze CHEN Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences Talk title: Live-seq Enables Temporal Transcriptomic Recording of Single Cells
	Haijun YU Shanghai Institute of Materia Medica, Chinese Academy of Sciences Talk title: Smart Nanomedicine for Cancer Immunotherapy	Xiaoyang ZHAO Southern Medical University Talk title: Understanding and Managing of Male Infertility Based on Mechanism Study
	Chengtie WU (Online) Shanghai Institute of Ceramics, Chinese Academy of Sciences Talk title: 3D Printing of Biomimetic Biomaterials and Cells
10:30-11:00	Coffee Break and Poster Session Venue: N2 – University Hall	Coffee Break and Poster Session Venue: N1 – Multi-function Hall
11:00-12:30	Session EIGHT Cell Death	Session NINE G protein-Coupled Receptor: Structure, Signaling, and Diseases
	Venue: N2 – University Hall	Venue: N1 – Multi-function Hall
	Session Chair(s) Hanming SHEN Faculty of Health Sciences, University of Macau	Session Chair(s) Leo Tsz On LEE Faculty of Health Sciences, University of Macau Session Co-Chair(s) Yang DU School of Medicine, Life and Health Sciences, The Chinese University of Hong Kong
	Liming SUN Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences Talk title: Necroptosis on the Brake	Yang DU School of Medicine, Life and Health Sciences, The Chinese University of Hong Kong Talk title: Structure, Function and Drug Disovery of G Protein-coupled Receptor in Nervous System
	Sudan HE Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College Talk title: The Role of RIPK1/RIPK3 in Inflammatory Responses Associated with GVHD	Sookja Kim CHUNG Faculty of Medicine, Macau University of Science and Technology Talk title: Exchange Proteins Activated by Cyclic AMP and Their Role in Diverse Function and Diseases
	You-Sun KIM Department of Biochemistry, Ajou University Talk title: Necroptosis: Molecular Mechanisms and Disease Implications	Hsien-Da HUANG School of Medicine, Life and Health Sciences, The Chinese University of Hong Kong Talk title: Multi-omics in MicroRNA-related Biomarker and Drug Target Discovery
	Francis Kaming CHAN Zhejiang University Medical Center Talk title: Immunogenic Cell Death: The Good, the Bad and the Ugly	Pei-Gen REN Shenzhen Institute of Advanced Technology, China Academy of Sciences Talk title: Development of Oral Polypeptide Drug Targeting GPRC6A for Nonalcoholic Steatohepatitis
		Yung Hou WONG Division of Life Science, The Hong Kong University of Science and Technology Talk title: Preferential Binding of G Protein to the MT1 Protomer of the MT1/MT2 Heterodimeric Melatonin Receptor Complex
12:30-14:30	Luncheon sponsored by Thermo Fisher Scientific (Hong Kong) Limited and Poster Session Venue: N1 – Multi-function Hall

16^th Jun 2023 (Fri) Day 3 – PM
14:30-16:30	Coffee Break and Poster Session Venue: N1 – Multi-function Hall
16:30-18:00	Session TEN Molecular Mechanism and Precise Diagnosis and Treatment of Cancer	Session ELEVEN Spatial Omics Biology
	Venue: N2 – University Hall	Venue: N1 – Multi-function Hall
	Session Chair(s) Kai MIAO Faculty of Health Sciences, University of Macau	Session Chair(s) Edwin CHEUNG Faculty of Health Sciences, University of Macau Peng WANG Faculty of Health Sciences, University of Macau
	Yuan LIU Institute of Basic Medicine and Cancer, Chinese Academy of Sciences Talk title: Nanoproteomics-based Biomarker Discovery and Cancer Diagnostics	Longqi LIU BGI Research Talk title: Large-field of View, High-Resolution Spatially Resolved Transcriptomics Using DNA Nanoball Patterned Array
	Jiangjiang QIN Institute of Basic Medicine and Cancer, Chinese Academy of Sciences Talk title: Targeting UPS for Cancer Therapy: New Mechanisms and New Strategies	Xianting DING School of Biomedical Engineering; Institute for Personalized Medicine, Shanghai Jiaotong University Talk title: Single Cell Proteomic Analysis Techniques and Clinical Applications
	Xiangsheng LIU Institute of Basic Medicine and Cancer, Chinese Academy of Sciences Talk title: Tumor Targeting Aptamer Drug Conjugate and Nano Drug Delivery System	Xiang ZHOU School of Public Health, University of Michigan Talk title: Statistical Methods for Spatial Transcriptomics
	Ji JING Institute of Basic Medicine and Cancer, Chinese Academy of Sciences Talk title: Design Optogenetic Toolbox for Deep Understanding Intracellular Organelles Communications and Remote Control of Programmed Cell Death

17 Jun 2023 (Sat)

17 Jun 2023 (Sat) Day 4 – AM
09:00-10:30	Session TWELVE TCM and Natural Product-based Drug Discovery	Session THIRTEEN Targeting Gut Microbiota and Metabolism for Cancer Immunomodulation
	Venue: N2 – University Hall	Venue: N1 – Multi-function Hall
	Session Chair(s) Xiuping CHEN Institute of Chinese Medical Sciences, University of Macau Ying WANG Institute of Chinese Medical Sciences, University of Macau	Session Chair(s) Elaine LEUNG Faculty of Health Sciences, University of Macau
	Hong PENG (Online) Yale University Talk title: Roles of University Technology Transfer in Biomedical Business	Xiang ZHANG Faculty of Medicine, The Chinese University of Hong Kong Talk title: Gut Microbiota, Metabolites and Fatty Liver Diseases
	Jinhua WANG (Online) The Institute of Materia Medica, Chinese Academy of Medical Sciences Talk title: The Study on Anti-Glioblastoma Effect and Its Mechanism of Sinomenine Ester Derivative	Yuting YANG on behalf of Hong WEI The First Affiliated Hospital, Sun Yat-Sen University Talk title: Humanized Germ-free Animal Models and Their Roles in the Study of Microbiome Related Tumor Genesis and Development and Immunotherapy
	Hubing SHI West China Hospital, Sichuan University Talk title: Immune Checkpoint HLA-E:CD94-NKG2A Mediates Evasion of Circulating Tumor Cells from NK Cell Surveillance	Di LIU Wuhan Institute of Virology, Chinese Academy of Sciences Talk title: Intestinal Microbiome and Disease Health
	Liwu FU Cancer Center, Sun Yat-Sen University Talk title: Progress in the Personalization of Tumour Chemotherapeutic Drug	Carmen Chak-Lui WONG School of Clinical Medicine, The University of Hong Kong Talk title: Precision Medicine and the Mechanistic Basis of Combination Treatments for Liver Cancer
	Hoi Leong Xavier WONG School of Chinese Medicine, Hong Kong Baptist University Talk Title: Therapeutic Targets of Metabolic Disorders- What’s New?
10:30-11:00	Coffee Break and Poster Session Venue: N2 – University Hall	Coffee Break and Poster Session Venue: N1 – Multi-function Hall
11:00-12:30	Session FOURTEEN Molecular Probes and Biosensors	Session FIFTEEN Neuroscience, Aging and Degenerative Diseases
	Venue: N2 – University Hall	Venue: N1 – Multi-function Hall
	Session Chair(s) Xuanjun ZHANG Faculty of Health Sciences, University of Macau Xiaoqiang CHEN College of Chemical Engineering, Nanjing Tech University	Session Chair(s) Wenhua ZHENG Faculty of Health Sciences, University of Macau Session Co-Chair(s) Jiangang SHEN School of Chinese Medicine, The University of Hong Kong
	Zhizeng GAO School of Marine Sciences, Sun Yat-Sen University Talk title: Development of Fluorescent Polarization-based High Throughput Screening Assays	Qing WANG Zhujiang Hospital of Southern Medical University Talk title: Neurovascular Unit Roles in Neurodegeneration
	Zonghai SHENG Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Talk title: Recent Advances in ICG Near-Infrared Fluorescence Molecular Imaging in the Second Biowindow	Xintong LIU Institute of Cerebrovascular Diseases, Guangdong No. 2 General Hospital Talk title: Research Progress in Prehospital Neuroprotection of Acute Stroke.
	Xiaoqiang CHEN College of Chemical Engineering, Nanjing Tech University Talk title: Functional Dyes for Imaging and Detection Applications	Xifei YANG Shenzhen Center for Disease Control and Prevention Talk title: Adiponectin Deficiency Accelerates Brain Aging via Mitochondria-associated Neuroinflammation
	Peng GUO Institute of Basic Medicine and Cancer, Chinese Academy of Sciences Talk title: Spatiotemporal Visualization of Bystander Activity of Antibody Drug Conjugates for Enhancing Solid Tumour Penetration	Haiwei HUANG The First Affiliated Hospital, Sun Yat-Sen University Talk title: Effect of Vestibular Dysfunction on Cognition
		Jiangang SHEN School of Chinese Medicine, The University of Hong Kong Talk title: Hypochlorous Acid Derived from Microglial Myeloperoxidase Mediates High-mobility Group Box 1 Release from Neurons to Amplify Brain Damage in Cerebral Ischemia-reperfusion Injury
12:30-14:30	Luncheon sponsored by LingBio Biotechnology Macau Company Ltd and Poster Session Venue: N1 – Multi-function Hall

17^th Jun 2023 (Sat) Venue: N2 – University Hall Day 4 – PM
Plenary Session TWO
Session Chair(s) Chuxia DENG Faculty of Health Sciences, University of Macau
14:30-15:10	Keynote Speaker: Dennis LO Faculty of Medicine, The Chinese University of Hong Kong Talk title: Creating Paradigms Shift in Molecular Diagnostics
15:10-15:40	Alexander HOFFMANN Microbiology and Immunology; The Institute for Quantitative and Computational Biosciences, University of California Talk title: A Temporal Signaling Code to Specify Immune Responses
15:40-16:10	Gourisankar GHOSH Department of Chemistry and Biochemistry, University of California San Diego Talk title: Diverse Nuclear Factors are Enablers of NF-kB’s Transcriptional Activity
16:10-16:40	Coffee Break
16:40-17:10	Hong ZHANG Institute of Biophysics, Chinese Academy of Sciences Talk title: Liquid–liquid Phase Separation in Autophagy
17:10-17:40	Richard J. YOULE National Institute of Neurological Disorders and Stroke, National Institutes of Health Talk title: Mitochondria Quality Control and Parkinson’s Disease
17:40-18:10	Short talk for poster
18:10-18:30	Best Poster Awards
	Closing Ceremony of the Ninth Macau Symposium on Biomedical Sciences
	Closing Speech by Prof. Renhe XU Associate Dean of the Faculty of Health Sciences of the University of Macau